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pidemiologists In The Spotlight

Pandemic Creates An Unofficial Who’s Who In Epidemiology Today

No other event in our lifetimes has called upon the knowledge, experience, and expertise of epidemiologists as frequently as the COVID-19 pandemic. Everywhere we turn, epidemiologists are forecasting estimated cases and deaths, being interviewed on television, writing editorials and op-ed articles, and answering questions for a wide variety of audiences. Never have epidemiologists been in such demand, even though we have more uncertainties than facts about the transmission dynamics and other epidemiologic features and parameters of COVID-19 at this point in time.

During these times, some epidemiologists have become darlings of the media and some considered heroes in providing reliable, objective, and trustworthy information to an anxious public  in various countries. Some have generated many new followers on Twitter. In monitoring the pandemic for our readers, we have collected a sample of contributions made by epidemiologists around the world. It constitutes an unofficial Who’s Who in Epidemiology today.


Value of Mitigation Applied Early

Britta Jewell, research fellow in the department of infectious disease epidemiology at Imperial College London and Nicholas Jewell, chair of biostatistics and epidemiology at the London School of Hygiene and Tropical Medicine and a professor at the University of California Berkeley, provide a graphic display of the impact social distancing can have, even if applied as little as one or two weeks earlier. According to their calculations based on a model developed by the Institute for Health Metrics and Evaluation, an estimated 90% of the cumulative deaths in the US between now and August 2020 might have been prevented by putting social distancing policies into effect on March 2, two weeks earlier than March 16, when there were only 11 deaths in the entire country. They also utilize the natural experiment of a delay of one week in Tennessee compared to Kentucky in implementing lockdown measures to illustrate clearly the impact of mitigation tactics applied earlier than later in an outbreak.  https://nyti.ms/2VDEyDZ


On CDC Disappearance

Thomas Frieden, former CDC Director published New York Times op-ed on April 12, 2020 writing “The CDC has the knowledge and expertise to limit the spread of the coronavirus, but it needs the authority and voice that‘s been withheld from it the past three months. It is not too late to limit the devastation of our nation’s health and economy. But the administration must support and follow the guidance of the CDC—and it must do so now.”   https://nyti.ms/2RNUP7X


Counting On Herd Immunity

Roman Prymula, a respected epidemiology expert in the Czech Republic has made headlines locally for making a surprising U-turn in favor of allowing the population to return to normal gradually to enable a controlled spread of COVID-19 and a gradual building of herd immunity while continuing to protect the vulnerable groups. He based his change of mind, as reported in the Czech media, because he believes China has provided incorrect data and the death rate in Italy is lower than initially calculated (not 15 percent but 2-3 percent).   https://bit.ly/2Kggm5c


Straight Talk and Hard Truths

Michael Osterholm, director of the Center for Infectious Disease Research and Policy at the University of Minnesota writing in the New York Times opinion page stating “It’s too late to avoid disaster, but there are still things we can do. Our leaders need to speak some hard truths and then develop a strategy to prevent the worst.”  https://nyti.ms/3eAm93i


Media Criticisms

Gregg Gonsalves, assistant professor of epidemiology at Yale, was the subject of an article at Fox News.com for criticizing New York Times reporters for the headline of a story they wrote suggesting there was an unsettled debate about the importance of testing for coronavirus. In an exchange of tweets after the story ran, Gonsalves said “Your collective reporting on the political aspects of this have been off-the-mark. Everything is a Punch & Judy show, and the real story of the absolute and continuing failure of the response to #coronavirus gets obscured in your reporting as “who’s winning the day” in DC. 


Need Infection Rate Information

Michael Mina, assistant professor of epidemiology at the Harvard School of Public Health and its Center for Communicable Disease Dynamics made a number of observations about the pandemic during a conference call with the media, according to the Harvard Gazette. Part of his advice was to get folks out of nursing homes because he believes the virus is much more transmissible than we have been able to document, and control in those circumstances is “an extraordinary feat.” He added  “We have to get to an order of magnitude understanding of how many people have actually been infected. We really don’t know if we’ve been 10 times off or 100 times in terms of the cases. Personally, I lean more toward the 50-100 times off, and that we’ve actually had much wider spread of this virus than testing…numbers are giving us at the moment.”


Government Fumbles

Larry Brilliant, an epidemiologist who worked internationally on smallpox eradication, co-founded Seva Foundation to treat eye disease in poor countries, led Google’s philanthropic efforts at one point, and helped create the movie Contagion to show what a serious pandemic could do to society was interviewed on April 1 for a podcast by The Economist.  

When asked if the governments are taking the pandemic seriously enough, he replied “I would say that governments have been incredibly slow in responding, almost without exception. I think that your government in the UK [...] began on a misguided mission to allow or think that they could allow everybody or a large number of people to become infected, in an effort to reach the epidemiologist’s Holy Grail of “herd immunity”.

I think my government [in America] fumbled, almost unforgivably, in the way they mangled the distribution of test kits; in the way that our leadership pretended that the outbreak could be brought down from five to zero and it would not be a problem after a while. And it continued to underplay how important it was, as “a hoax,” until finally confronted with the stark reality.”   https://econ.st/2Kif4GK

Brilliant was also interviewed for the podcast Soul of the Nation on a moral response to COVID-19.     https://bit.ly/3bjXwpP



High Profile in China

Zhong Nanshan, is being called China’s leading epidemiologist sometimes referred to as the nation’s “SARS hero” by Chinese media, according to The Diplomat, a publication covering the Asia Pacific region. In 2003, while SARS left China’s health authorities and government officials struggling to rebuild public trust, Zhong was hailed for his integrity. This was largely due to his public admission that the virus was not as under control as state media portrayed.

The Diplomat reports that “Despite his advanced age (born in 1936) Zhong has been appointed to lead the National Health Commission’s investigation into the novel coronavirus. By extension, he has become the de facto spokesperson for any information related to the illness. Beyond his work tracking and studying COVID-19, he has given multiple interviews to Chinese and English language media. He is an obvious choice for the position, as the Communist Party tries to highlight its efforts to manage the crisis in a transparent, decisive manner…”  https://bit.ly/3eAnebm


Epi Predictions

Marc Lipsitch, Harvard professor of epidemiology and director of the School’s Center of Communicable Disease Dynamics has been in the news for the COVID-19 projections his academic group have provided that intermittent social distancing may be needed until 2022. In an informative interview in USA Today, Lispsitch said we’re in a dilemma—if we relax the restrictions we can expect a resurgence, and if we keep the restrictions in place it will be economically disastrous. What to do? He thinks we can try to bring down cases in each locality to a point where they can be controlled individually. But the epidemic will likely appear in more than one wave and people are confused about that thinking if you stop it once you’re done.

Asked directly, so how long will people have to hunker down? Lipsitch said “It’s not a scientific choice only. It’s ultimately a political choice, and science is one input.” Asked, so how do you see things playing out, Lipsitch gave his longest reply—

“If I had to make a prediction about how the interaction between social and scientific and public health factors will play out, I think there's going to be fatigue at some point. Some places are going to let up either after they've controlled the first peak or before they've controlled the first peak. Cases will reemerge, and because people are so tired of social distancing, it will take until the intensive care units are overwhelmed in that place to get people to crack down again, and then there will be some cycles of that. There are ways to try to avoid that, but they all involve this very long and destructive process of social distancing. It's easy to say as the public health person, this is what we need to do for public health. But I'm acutely aware that there are also other considerations, and I don't see a really good answer.”


Controversy In Sweden

Anders Tegnell, Sweden’s chief epidemiologist and reportedly the architect of his country’s “social distancing light” or “soft” approach (allowing population immunity to develop more naturally) has been fending off critics.  Sweden sought to shelter the elderly and vulnerable but has left stores and offices open and waiting to see what happens. According to the European Centers for Disease Control and Prevention, Sweden has reported over 1200 deaths through April 16 compared to only 72 in Finland with half the population which is often used as a comparison because it took more stringent measures in the Helsinki area. Other Scandinavian countries have also reported significantly fewer deaths with rates per 100,000 much lower.

Joacim Rocklov, a professor of epidemiology at Umea University is quoted in the Wall Street Journal saying “this is a big risky experiment with the entire population that could have a catastrophic outcome…It is risky to leave it to people to decide what to do without any restrictions…”

A recent op-ed in one of the important newspapers by 22 physicians urged the government to lockdown the country as is being done elsewhere. Tegnell has rejected these arguments and has debated critics, according to a recent account in Canada’s National Post. It concludes by saying about Tegnell, “One wishes good luck to the temporary helmsman of the Swedish ship of state as he argues that icebergs are not really his department.”   https://on.wsj.com/2RKqmru


Burden Unimaginable

After offering to come out of retirement to help with COVID-19 control efforts, Bill Hall's offer was immediately taken up by his former health department. He told local media “I am a roving epidemiologist. What that means is that I’m available to travel to whichever district in the Eastern Region of the state that is in the greatest need of epi manpower. According to the paper Hall spends his days interviewing COVID-19 patients and their contacts; trying to locate contacts who might have been exposed to the virus; and doing patient followups, case reviews, case monitoring, and data entry, among other tasks. Additionally, he provides guidance to health care facilities and physicians about testing criteria.


He said “The burden created on the health care and public health system is unimaginable…My hat just goes off to all the people who are doing all this work.”


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