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Experts Speak Out On The Current Status of the Pandemic In The US

Everyone Wants To Know--Where Do We Go From Here? How Does This End?

The steady decline of cases, hospitalizations, and deaths attributable to COVID-19 has created a proliferation of interviews and articles seeking to explain and to predict the trajectory of the pandemic from this point forward.

Undercount

In the US, some have asserted the decline in the pandemic is due to vaccination or  having achieved certain level of herd immunity because of the estimated number of persons in the US who have already been infected. For example, a study out of Columbia University led by Jeffrey Shaman estimates that the number of active cases of COVID-19 is ten times higher than the number of confirmed cases on any given day. According to this computer model, an estimated one third of the US population has already been infected.

Current Status

One of the most informative sources continues to be the Institute for Health Metrics and Evaluation which has recently issued policy briefings about its predictions for each region of the world and some individual countries.

In the latest briefing for the US dated late February, IHME asserts that the main driver for the decline in the US is seasonality aided by expanding levels of vaccination. Reported mask use remains high at 77%. In contrast to the Columbia model, the IHME estimates that only 18% of people in the US have been infected as of mid-February.

Michigan Example

In Michigan where the declines have been very marked, one report identified cold weather and decreased mobility as factors explaining the drop. Other reasons included people double-masking or wearing more effective masks. In Michigan, vaccination levels were not considered high enough yet to explain the declining rates. An estimated 15% of Michigan residents have had coronavirus.

Projections

In seeking to predict the trajectory of the pandemic over the short term between now and next summer, IHME notes that the B.1.1.7 coronavirus variant is expected to increase from 20% of infections today to 80% by late April. Most important in projecting cases over the near term is actually the behavior of Americans. According to IHME, “If most individuals remain careful, maintaining mask-wearing through April or longer we expect…a cumulative death toll of 589,000. More rapid increases in mobility or reductions in mask use can easily lead to increasing cases and deaths in many states in April…

...Managing the epidemic in the next four months depends critically on scaling up vaccination, trying to increase the fraction of adults willing to be vaccinated above three quarters, and strongly encouraging continued mask use and avoiding situations where transmission is likely, such as indoor dining, going to bars, or indoor gatherings with individuals outside the household. Despite the favorable trends in the epidemic we do not expect to reach herd immunity prior to next winter.”

Normalcy

The steep declines in cases, hospitalizations, and deaths are also fueling discussion about how the pandemic will end and when we can return to normal life. A recent feature article in the Atlantic queried a variety of experts to get their opinions about what life will be like over the next four seasons. Bottom line—the article summarizes its prediction by stating “an uncertain spring, an amazing summer, a cautious fall and winter, and then finally, relief.”

This assessment has a lot to do with the uncertainty about the impact the virus variants will have this spring and the expectation that vaccinations and warmer weather will allow many aspects of life to return to normal this summer, but not the return of indoor concerts, dining in at crowded restaurants, full attendance at large sporting events, and international travel. Taking the longer view requires making assumptions about the impact of the variants and the ability to adjust vaccines to keep them effective. In the longer term, the article guesses that the coronavirus will be less lethal and more like the flu during the colder months but without wide uncontrolled spread.

White House Take On Future

Leaders of the White House pandemic effort recently took part in a conversation sponsored by the American Public Health Association and the National Academy of Medicine entitled “A New Year of COVID: The State of the Pandemic and U.S. Strategy in 2021”. Speakers included CDC’s new Director Rochelle Walensky, Marcella Nunez-Smith, Chair, COVID-19 Equity Task Force, and Andy Slavitt, White House Senior Advisor on COVID-19 Response. Georges Benjamin, APHA president and moderator asked how is the administration thinking about how this ends?  He noted there's several possible futures from endemic disease to seasonal disease to this being a false reduction and getting another fourth surge. 

No Crystalballing

Nunes-Smith resisted the idea of using a crystal ball to project how and when we get to our new normal. She answered as follows “What we know now is that we have the benefits of great scientific discovery and breakthrough in the authorized vaccines and quite frankly in the therapeutics that are underutilized...

...We have tools in the toolbox.  We know basic health things that work.  Masking, still socially distancing, all of that.  So I think it is early to say exactly where we will end up and will we end up with an endemic sort of COVID-19.  What we do know is that our immediate issue is to try to reduce pressure on the virus to mutate in ways that are clinically significant.  And the best way we can do this is to be efficient and equitable in our vaccination work.”

As leader of the White House response, Slavitt suggested”…we have to have much better real-time ability to see what's happening, where it's happening and to react to it. Second is, we have to do scenario planning …We can all wish for this to be the last wave.  But we wouldn't be doing our jobs if we weren't actively focused on containment measures for the variants, if we weren't actively focused on how might therapeutics help to minimize the effect of the variants.  How might we make sure that if we do have another wave it feels different?

...So all of this to say the question you're asking is a good one.  And as Dr. Nunez-Smith said, we won't predict the future internally, we do feel like we have to prepare for each of those scenarios and also not try to answer the unknowable questions.”

 

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