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Multiple Proposals Being Made For Going Forward Against COVID-19

Despite the success of ongoing mitigation or social distancing measures in dampening the spread of COVID-19, the strategy’s high social and economic costs have brought forth a flurry of new proposals for how best to control or even eliminate the disease from this point forward.

How We Got Here

After the first appearance of the COVID-19 cases in the US, the initial control strategy was to test ill persons to identify and treat cases, trace exposed contacts, and quarantine persons when indicated. This containment strategy failed to stop the chains of transmission stemming from the earliest imported cases. This occurred for a variety of reasons, including the fact that not all infected persons were symptomatic, and testing with rapid results was not widely available.

As community transmission took hold, the fear that hospitals and other providers would be overwhelmed and that deaths would rise even higher encouraged or even necessitated the use of severe social distancing measures to slow the rate of spread even at the cost of severe economic impact. This mitigation strategy has been widely referred to as flattening the epidemiologic curve. It sought to buy time for hospitals, health care workers, first responders and other service providers by slowing the demand for services and thereby preventing deaths that would have occurred in a completely overwhelmed health system.

Not all countries bought into these containment or mitigation strategies as the best approaches.

Different Approaches

 Sweden took a much less restrictive approach with the idea of allowing the population to acquire disease and create a level of population immunity that might become high enough to provide herd immunity against future outbreaks. The United Kingdom also gave consideration to this approach early on until epidemiologic models predicted that this strategy without social distancing measures could produce half a million deaths.  The same models predicted over 2 million deaths in the US without aggressive social distancing measures and reportedly influenced the US decision to undertake widespread mitigation. These model estimates of expected deaths have subsequently been lowered to reflect the new realities created by implementation of strict measures in the UK and the US.

Crushing The Curve

New Zealand took a more extreme strategy to not merely flatten the curve but to crush the curve. The goal here was to implement such strict measures that the imported virus could actually be eliminated and future importations blocked or new chains of transmission contained through testing, contact tracing, and quarantine.

Current Situation

Now that mitigation efforts have proven effective in slowing spread in in several of the viral hotspots where SARS-CoV-first appeared, some of the negative impacts on the economy and the quality of life in the US have become clearer. It is apparent that the restrictions imposed by the social distancing strategy must be eased at some future point and discussions have intensified about what the best way forward might be and what the optimum balance is of public health and economic and social measures. Making these choices will be fraught with uncertainties about the new virus such as whether it will exhibit seasonality or whether it will occur in additional future waves of infection.

Lives Saved Do Far

 A recent Wall Street Journal investigation reports that mitigation efforts in the US have saved more than 100,000 lives by mid-April and will have saved 500,000 lives by the end of the month. Putting the statistical value of a life at $10 million, the benefits of mitigation equalled an estimated  $1 trillion by mid-month and $5 trillion by end of April. A second estimate in the report is that social distancing is saving 1.7 million lives worth $8 trillion for three months of social distancing. The cost to the economy is estimated at $3 trillion through 2022 and the article calls this trade-off worth it in an accounting sense. These estimates are derived in part from the work of Alessandro Vespignani and his team of modellers at Northeastern University. He told the WSJ, “The decisions that will be made in the next few weeks must include economists and epidemiologists and public health people to find the trade-off between those two viewpoints.”

Articles in this issue of the Epidemiology Monitor provide details about some of the new proposals being circulated. 
 


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